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KMID : 0377520150400040075
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Chung-Ang Journal of Medicine
2015 Volume.40 No. 4 p.75 ~ p.79
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Clinical Outcomes of the Patients with Multiple Myeloma According to the Two Different Staging Systems
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Hyun Sun-A
Kang Je-Wook
Ryu Hyong-Kyu
Kim Yu-Jeong
Park Jin-Woong
Noh Choong-Kyun
Lee Young-Soo
Park Joon-Seong
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Abstract
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Background: International staging system (ISS) has become popular because of its simplicity compared with Durie-Salmon system (DSS) for myeloma. However, accurate clinical outcome should be clarified when a patient presents different stage according to the two different staging system.
Method: A total of 85 consecutive myeloma patients were evaluated their clinical outcomes after treatment at Ajou University Hospital between 2004 and 2013.
Result: Among ISS I patients, the overall survival (OS) of DSS II and DSS III was 51.2 and 52.2 months, respectively. In ISS-II patients, the OS of DSS I and DSS III was 48.1 and 38.7 months, respectively. In ISS III patients, the OS of DSS I and DSS II was 8.2 and 17.1 months, respectively. All of the values were not significant.
Conclusion: Our data indicated that subdivision by DSS did not affect survival outcomes of patients who presented same stage by ISS. Enough sample size with homogenous treatment is necessary in order to support this result.
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KEYWORD
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iple myeloma, Neoplasm staging
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